A typical workflow in sensor development for breath diagnostics might look something like this:
- Stage 1: Can the sensor detect the compound of interest?
- Stage 2: Can the sensor detect the compound at the required concentration levels?
- Stage 3: Can the sensor still detect the compound in a background of other compounds typically found in breath?
- Stage 4: Can the sensor detect the compound if the sample is also at humidity levels representative of breath?
- Stage 5: Can the compound be detected in a sample of real human breath?
- SiHuB allows each of these stages to be performed in turn. In steps 1&2, the output from a single vapor generator provides a controllable concentration of the compound under investigation. In stage 3, combining the outputs of multiple vapor generators allows a matrix of gases approximating the makeup of human breath to be generated. In stage 4, a humidity generator is used to add humidity to the gas mixture. Finally, in stage 5, the sensor is ready for testing with real breath samples, collected by a sampler such as the ReCIVA.