MicroNIR PAT-W

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The MicroNIR PAT-W spectrometer is a fit-for-purpose near-infrared (NIR) analyzer for quality-by

-design (QbD) manufacturing. The spectrometer is a sturdy, scalable, next-generation system for

real-time process monitoring in blend homogeneity, content uniformity, loss on drying, roller

compaction, and similar process analytical technology (PAT) applications.

 

With the well-established Viavi linear variable filter (LVF) technology, the PAT-W has the smallest

form factor among commercial process monitoring instruments in a fit-for-purpose design.

This makes it ideal for use with processing equipment of a variety of sizes, with the stability and

performance to facilitate efficient and smart manufacturing.

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The user-friendly MicroNIR PAT-W was engineered to handle today's challenging GMP-regulated environments yet requires minimal system maintenance. There are no expensive fiber optic cables or moving components, enabling superior instrument stability and performance in challenging process environments.

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Features and Benefits

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The key features of the MicroNIR PAT-W spectrometer are as follows:

• Non-destructive, non-invasive, and real-time near-infrared analysis

• User-selectable Ethernet or Wi-Fi for data communication and system control

• User-replaceable, rechargeable Li-ion battery with over eight hours of uninterrupted run time

• Integrated PC enables fast and secure store and forward of spectral data

• Incorporated multi-axis orientational triggering

• Trigger options for a variety of applications: push button, OPC and external photosensor

• Real-time moving block standard deviation (MBSD) analysis for endpoint determination in granulation, blending, drying, and coating processes

• Washable, IP65/67-rated enclosure

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Applications

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Pharmaceutical Manufacturing

• Blend & content uniformity

• Fluid bed drying

• Granulation​

Food and Feed Manufacturing

• Moisture content

• Nutritional assay

• Protein, fat & fiber

 

Industrial Processing

• Polymers

• Reaction monitoring

• Petrochemicals

 

Software

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The included MicroNIR Pro software suite has features for data acquisition, calibration and method development, user management, and real-time prediction. MicroNIR Pro can build and apply complete chemometric models using regression and classification algorithms including PLS, Moving Block, SMV, and PCA analyses. Batch mode predictions on stored data are also supported.

Options include an enhanced OPC interface for integration with process control systems and prediction engine add-ins for Camo Unscrambler, Eigenvector Research Solo Predictor and Sartorius SIMCA chemometric software.

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Specifications

• Illumination source: Two integrated vacuum tungsten lamps

• Bulb life: >40,000 hours

• Illumination geometry: Flood illumination/ 0° observer

• Input aperture dimensions: 2.5 x 3.0 mm

• Sample working distance: 0-15 mm from window

• Dispersing element: Linear variable filter

• Detector: 128-pixel InGaAs photodiode array

• Pixel size/pitch: 30 µm x 250 µm/50 µm

• Wavelength range: 950 – 1650 nm (10,526 – 6060 cm-1)

• Pixel-to-pixel interval: 6.2 nm for 950-1650 nm

• Spectral bandwidth (FWHM): <1.25% of center wavelength (1% typical) (for example, @1000 nm, resolution is <12.5 nm)

• Analog-to-digital Convertor: 16 bit

• Dynamic range (max): 1000:1

• Measurement time (typical): 0.25 – 0.5 second

• Integration time: 10 ms typical, minimum 10 µsec, maximum limited by dark signal

• Computer interface: TCP/IP Cat5 Ethernet 802.11 g WiFi

• Spectrometer weight: Less than 1.4 kg (3 lb)

• Size: 160 mm x 136 mm x 136 mm (6.3 in x 5.37 in x 5.37 in)

• Power: Battery: 7.5 V @6.4 Ah for >8 hr run time External: 110-240 V AC

• Data format: Encrypted, Unsb, CSV, and SPC output

• Operating system: Windows 8.1, 8, and 7

• Software available: MicroNIR PAT, Unscrambler X Lite, MicroNIR Process

• Operating temperature: 0 – 40 deg C (non-condensing)

• Enclosure: Stainless steel and aluminum: dust and waterproof, sealed and cleanable to IP67 standard

• Trigger: Internal 9-axis IMU, external 24 V input

• Mounting: Adaptable stainless steel tri-clover mount